Exosome Profiling

Exosomes have been implicated in numerous biological processes, and they may serve as important disease markers. Surface proteins on exosomes carry information about their tissues of origin. Because of the heterogeneity of exosomes, it is desirable to investigate them individually. Lihan biologics provides various assays to profile surface proteins of individual exosomes using specialized methods:

  • Antibody-DNA conjugates and next-generation sequencing
  • DNA-assisted immunoassays
  • Proximity ligation or extension assays
  • Multiple-recognition proximity ligation assay (4PLA)
  • Exosomal cytokines profiling
  • Exosomal RNA isolation and qPCR analysis
  • Exosomal protein isolation and profiling
  • Exosomal cDNA isolation and profiling